Actually I learned to live with the loop as it is. But I've have always wondered how would things go if I put a Boss Line Selector as a "buffer" to the loop. It is an easy try I'll have to do some of these days... got to find the time.

I use this loop trough a long stereo cable, that splits into send-return at the pedalboard on an hammond box. I'm sure there is some tone loss there. I compesate it a little with the TimeFactor as it has line/guitar level on inputs and outputs.

But, being honest, I've noticed stronger tone "loss" caused by pedals in front of the amp, rather than the loop the way I use it. When you go trough pedals, there is always a compromise somehow...